Chronic renal failure mcq. 1 CODE: MG1.1.1 COURSE: Anatomy – Embryology ... - Gr.T. Popa


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Chemical A benzyl isoquinolonium ester. It is a short-acting relaxant which is rapidly broken down by the body. This makes atracurium very predictable, as it wears off rapidly compared with the longer-acting relaxants.

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Cardiovascular effects Although atracurium produces few direct circulatory effects, the absence of vagal blocking activity makes the patient vulnerable to bradycardias during anaesthesia. Histamine release gejala papilloma virus occur with doses of atracurium greater than 0.

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Histamine may also be released if atracurium precipitates in the syringe or vein. This may occur if atracurium is injected immediately after thiopentone.

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Respiratory effects In standard doses, atracurium rarely causes problems with bronchospasm. Bronchospasm can occasionally occur secondary to histamine release.

Placental transfer is insignificant and the drug is widely used in obstetrics. Distribution, metabolism and excretion Atracurium is broken down to inactive metabolites by minor ester hydrolysis and spontaneous Hoffman elimination major pathway to Laudanosine.

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There is little change in its effects in patients with renal or liver failure. When used for long operations, it is very predictable. Dose, administration and use A dose of 0.

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Supplemental doses should chronic renal failure mcq mg. Contraindications Atracurium precipitates in an alkaline pH and it should never be mixed with thiopentone.

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Always flush the vein with saline if using the two drugs at induction. Storage Should be kept in a refrigerator at 4 degrees C, as the drug deteriorates at room temperature. Reference Early neuromuscular blockade in the acute respiratory distress syndrome.

The study of biochemistry provide the fundamental knowledge of metabolisms through which the normal function of the organism occurs. It also assure knowledge of the pathways through which diseases and pathological processes appear. Proteins Aminoacids — structure, properties;Peptides; Proteins — structure primary, secondary, tertiary, cuaternaryproperties, classification; cromoproteins- mioglobine, hemoglobin, citocroms structure; nucleoproteins — nitrogen basis, nucleosides, nucleotides, nucleic acids structure ; Free nucleotides Enzymes. Tricarboxilic acids cycle; Microsomal system of oxidation Cit. P Glucidic metabolism.

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